MetalBindProtPlantV1, Main, Exploration, bibRecord, 000246

Phytochelatins inhibit the metal-induced aggregation of alpha-crystallin.

Identifieur interne : 000246 ( Main/Exploration ); précédent : 000245; suivant : 000247

Phytochelatins inhibit the metal-induced aggregation of alpha-crystallin.

Auteurs : Yasuhisa Hori [Japon] ; Tomoaki Yoshikawa ; Naoki Tsuji ; Takeshi Bamba ; Yoshikazu Aso ; Motonori Kudou ; Yoshiki Uchida ; Masahiro Takagi ; Kazuo Harada ; Kazumasa Hirata

Source :

Journal of bioscience and bioengineering [ 1347-4421 ] ; 2009.

RBID : pubmed:19217556

Descripteurs français

KwdFr :
- Cristallines alpha (antagonistes et inhibiteurs), Cristallines alpha (physiologie), Métaux (métabolisme), Phytochélatines (pharmacologie).
MESH :
- antagonistes et inhibiteurs : Cristallines alpha.
- métabolisme : Métaux.
- pharmacologie : Phytochélatines.
- physiologie : Cristallines alpha.

English descriptors

KwdEn :
- Metals (metabolism), Phytochelatins (pharmacology), alpha-Crystallins (antagonists & inhibitors), alpha-Crystallins (physiology).
MESH :
- chemical , antagonists & inhibitors : alpha-Crystallins.
- chemical , metabolism : Metals.
- chemical , pharmacology : Phytochelatins.
- chemical , physiology : alpha-Crystallins.

Abstract

Phytochelatins (PCs) are heavy-metal-binding peptides found in some eukaryotes. This study investigates the use of plant-derived PCs for the inhibition of metal-induced protein aggregation. The results of this study show that PCs inhibit zinc-induced alpha-crystallin aggregation, and suggest that PCs might be useful as anti-cataract agents.

DOI: 10.1016/j.jbiosc.2008.09.021
PubMed: 19217556

Affiliations:

Japon

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000253
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Le document en format XML

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<author><name sortKey="Hori, Yasuhisa" sort="Hori, Yasuhisa" uniqKey="Hori Y" first="Yasuhisa" last="Hori">Yasuhisa Hori</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Environmental Biotechnology, Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan. hori@phs.osaka-u.ac.jp</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Environmental Biotechnology, Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871</wicri:regionArea>
<wicri:noRegion>Osaka 565-0871</wicri:noRegion>
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<author><name sortKey="Yoshikawa, Tomoaki" sort="Yoshikawa, Tomoaki" uniqKey="Yoshikawa T" first="Tomoaki" last="Yoshikawa">Tomoaki Yoshikawa</name>
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<author><name sortKey="Tsuji, Naoki" sort="Tsuji, Naoki" uniqKey="Tsuji N" first="Naoki" last="Tsuji">Naoki Tsuji</name>
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<author><name sortKey="Bamba, Takeshi" sort="Bamba, Takeshi" uniqKey="Bamba T" first="Takeshi" last="Bamba">Takeshi Bamba</name>
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<author><name sortKey="Aso, Yoshikazu" sort="Aso, Yoshikazu" uniqKey="Aso Y" first="Yoshikazu" last="Aso">Yoshikazu Aso</name>
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<author><name sortKey="Kudou, Motonori" sort="Kudou, Motonori" uniqKey="Kudou M" first="Motonori" last="Kudou">Motonori Kudou</name>
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<author><name sortKey="Uchida, Yoshiki" sort="Uchida, Yoshiki" uniqKey="Uchida Y" first="Yoshiki" last="Uchida">Yoshiki Uchida</name>
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<author><name sortKey="Takagi, Masahiro" sort="Takagi, Masahiro" uniqKey="Takagi M" first="Masahiro" last="Takagi">Masahiro Takagi</name>
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<author><name sortKey="Tsuji, Naoki" sort="Tsuji, Naoki" uniqKey="Tsuji N" first="Naoki" last="Tsuji">Naoki Tsuji</name>
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<author><name sortKey="Kudou, Motonori" sort="Kudou, Motonori" uniqKey="Kudou M" first="Motonori" last="Kudou">Motonori Kudou</name>
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<author><name sortKey="Uchida, Yoshiki" sort="Uchida, Yoshiki" uniqKey="Uchida Y" first="Yoshiki" last="Uchida">Yoshiki Uchida</name>
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<series><title level="j">Journal of bioscience and bioengineering</title>
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<term>alpha-Crystallins (physiology)</term>
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<term>Cristallines alpha (physiologie)</term>
<term>Métaux (métabolisme)</term>
<term>Phytochélatines (pharmacologie)</term>
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<front><div type="abstract" xml:lang="en">Phytochelatins (PCs) are heavy-metal-binding peptides found in some eukaryotes. This study investigates the use of plant-derived PCs for the inhibition of metal-induced protein aggregation. The results of this study show that PCs inhibit zinc-induced alpha-crystallin aggregation, and suggest that PCs might be useful as anti-cataract agents.</div>
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<name sortKey="Harada, Kazuo" sort="Harada, Kazuo" uniqKey="Harada K" first="Kazuo" last="Harada">Kazuo Harada</name>
<name sortKey="Hirata, Kazumasa" sort="Hirata, Kazumasa" uniqKey="Hirata K" first="Kazumasa" last="Hirata">Kazumasa Hirata</name>
<name sortKey="Kudou, Motonori" sort="Kudou, Motonori" uniqKey="Kudou M" first="Motonori" last="Kudou">Motonori Kudou</name>
<name sortKey="Takagi, Masahiro" sort="Takagi, Masahiro" uniqKey="Takagi M" first="Masahiro" last="Takagi">Masahiro Takagi</name>
<name sortKey="Tsuji, Naoki" sort="Tsuji, Naoki" uniqKey="Tsuji N" first="Naoki" last="Tsuji">Naoki Tsuji</name>
<name sortKey="Uchida, Yoshiki" sort="Uchida, Yoshiki" uniqKey="Uchida Y" first="Yoshiki" last="Uchida">Yoshiki Uchida</name>
<name sortKey="Yoshikawa, Tomoaki" sort="Yoshikawa, Tomoaki" uniqKey="Yoshikawa T" first="Tomoaki" last="Yoshikawa">Tomoaki Yoshikawa</name>
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	Serveur d'exploration sur les protéines de liaison chez les plantes
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Serveur d'exploration sur les protéines de liaison chez les plantes

Phytochelatins inhibit the metal-induced aggregation of alpha-crystallin.

Phytochelatins inhibit the metal-induced aggregation of alpha-crystallin.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki